Medicines

Article 1: https://www.popsci.com/injectable-biomaterial-stops-you-bleeding-out/

Article 2: https://news.psu.edu/story/351700/2015/04/06/research/sound-separates-cancer-cells-blood-samples

          The article “Engineer better Medicines” discusses how eengineers are developing new systems to innovate and personal the medical delivery system. Personal Medicine’s are intended be more efficient as it attends to the patients personal DNA coding. Everyone’s reaction to a most anything from food to disease and drug differs due to difference in our DNA coding. The challenge engineers are currently facing towards creating personalized medicine are caused by our a large population making difficult to collect and assess everyones specific data.

          “Injectable Enzyme Stops Wounds From Bleeding” by Alexandra Ossola addresses the possible use of an injectable material that can help blood clot faster and more effectively. This is done by plugging up the wound to stop the bleeding. Researchers at the University of Washington have created a synthetic material which can be injected when a person is losing a lot of blood. A material called PolySTAT is able to mimics the body’s enzyme Factor XIII, which essentially helps the fibrin strands cement a blood clot. In a separate test on rats that had a major wound in one of their arteries, the researchers found that the rats that did not receive an injection of said PolySTAT lost up to 11 times more blood than the rats treated with PolySTAT.

         “Sound separates cancer cells from blood samples” by A’ndrea Elyse Messer speaks on the use of a acoustic tweezer in order to separating cancer cells from blood cells. Acoustic-based separations are important because they are a non-invasive alternative and do not alter or damage cells. According to the article, in order to be effective for clinical use, they also need to be rapidly and easily applicable. “In order to significantly increase the throughput for capturing those rare CTCs, device design has to be optimized for much higher flow rates and longer acoustic working length,” said Ming Dao the principal research scientist and engineer at MIT. she goes on to explain that the new generation of the device has implemented an integrated experimental/modeling approach, which has improved cell sorting throughput more than 20 times higher already and has now made it possible for the researchers to work with patient samples.